Is isotretinoin safe in 2026? A UK dermatologist explains
This is one of the most common questions I get. Usually asked with a slightly worried expression and often followed by something like, “I’ve read some things online…” So let’s clear this up properly.
By Dr Sreedhar Krishna, Consultant Dermatologist
Yes, isotretinoin is safe in 2026 when it is prescribed and monitored correctly. In fact, it remains one of the most studied and well understood treatments we use in dermatology.
The drug itself has not changed much over the years. What has changed is how carefully we prescribe it and how well we understand who it is right for.
Why isotretinoin still has a reputation
Isotretinoin has always been a powerful medication. Because of that, it has always come with rules. Over time, those rules have sometimes turned into fear rather than facts.
In reality, most patients experience predictable and manageable side effects such as dry lips, dry skin, or mild muscle aches. Anyone starting isotretinoin should buy lip balm early. That is not medical advice. It is survival advice.
Serious side effects are rare, particularly when patients are properly assessed and monitored.
What makes isotretinoin safer in 2026
In the UK today, isotretinoin prescribing involves:
- Careful screening before starting
- Clear pregnancy prevention guidance where relevant
- Blood tests when appropriate
- Regular follow-up during treatment
These steps are not there to make life difficult. They exist because they work.
Can isotretinoin be prescribed online?
It can be, but only if the same standards are applied as they would be in a clinic.
That means a proper consultation, a medical history, safety counselling, and follow-up. Online prescribing should never mean rushed prescribing.
When done properly, online isotretinoin treatment can be both safe and convenient.
In short: isotretinoin is not something to fear. It is something to respect. Used properly, it remains one of the most effective treatments we have.